唐人街神探唐仁（王寶強飾）和秦風（劉昊然飾）前往東京加入日本探員野田昊（妻夫木聰飾）調查一件受到高度矚目，有權有勢的企業家謀殺案件 － 而嫌疑最大的殺人犯就是殺人不眨眼的黑龍幫幫主。但是受到指令調查本案的其實不只他們三人，來自全球偵探排名榜 “CRIMASTER World Detective Rankings” 的頂尖偵探也在東京集結，聯合偵辦此案。當世界級超級偵探 “Q” 出現時，不但令兩人破案的心情更為迫切，也令唐仁和秦風更覺得疑心重重。他們一頭撞進這場心驚膽顫的挑戰中，加入全亞洲最頂尖的偵探一起破案

Chinatown detectives Tang Ren (Wang Baoqiang) and Qin Feng (Liu Haoran) head to Tokyo to join Japanese investigator Noda Hiroshi (Satoshi Tsumabuki) on a high-profile case involving the murder of a powerful businessman… and the prime suspect is the president of the lethal Black Dragon Gang. But they’re not the only ones taking on the challenge, as detectives from “CRIMASTER World Detective Rankings” also converge in Tokyo to help catch the killer. The appearance of the number one-ranked super-sleuth “Q” on the scene raises the stakes and makes the case even more suspicious for Tang Ren and Qin Feng, who are plunged headlong into the ultimate challenge as the strongest detectives in Asia join forces and fight it out to crack the case.